Evidence & regulatory context
- Mechanism
- Not recorded
- Target
- Not recorded
- Injury models
- TBI
- Reported indication
- Not recorded
- First approval
- Not recorded
- Development stage
- Not recorded
- ChEMBL record
- Not recorded
- ChEMBL max phase
- Not recorded
- Synonyms
- Not recorded
- Note
- Not recorded
Clinical trials 10
1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
A Follow-up Study to Evaluate the Safety for the Patients With ALLO-ASC-DFU Treatment in Phase 2 Clinical Trial of ALLO-ASC-BI-201
Burn
Enrolment: 14 · Results not recorded
A Phase 2A Randomized, Placebo-Controlled Study of Intravenous Allogeneic Adipose-Derived Mesenchymal Stem Cells to Treat Post COVID-19 Pulmonary Compromise
Covid19
Enrolment: 0 · Results not recorded
Treatment of COVID-19-Induced Acute Respiratory Distress: A Phase 2 Study of Intravenous Administration of Allogeneic Adipose-Derived Mesenchymal Stem Cells
Covid19 · ARDS
Enrolment: 0 · Results not recorded
Phase Ib/IIa Clinical Trial to Assess the Safety of i.v. Administration of Allogeneic Adipose-derived Mesenchymal Cells (eASCs) to Refractory Rheumatoid Arthritis Patients
Rheumatoid Arthritis Aggravated
Enrolment: 53 · Results not recorded
Phase I/II Clinical Trial to Assess Safety and Efficacy of Intravenous Allogeneic Expanded Adipose Tissue Mesenchymal Stem Cells in Patients With Severe Pneumonia Due to COVID-19
Sars-CoV2
Enrolment: 26 · Results not recorded
Phase I Study of Allogeneic Adipose-derived Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome
ARDS
Enrolment: 20 · Results not recorded
Bone Marrow-Derived Mesenchymal Stem Cell Therapy for Chronic Kidney Disease
Chronic Kidney Diseases
Enrolment: 14 · Results not recorded
Phase I Clinical Study to Evaluate Safety and Efficacy of ANT-301 in Knee Osteoarthritis Patients
Osteoarthritis, Knee
Enrolment: 6 · Results not recorded
Hip RECLAIM: A Phase I Safety and Feasibility Trial of REcycled CartiLage Auto/Allo IMplantation for Focal Hip Cartilage Defects
Cartilage Defect
Enrolment: 15 · Results not recorded
Expanded Access Protocol to Evaluate Allogeneic HB-adMSCs for the Treatment of Multiple System Atrophy
Multiple System Atrophy
Enrolment not recorded · Results not recorded
Preclinical evidence 1
1 studies reported at therapy level; 1 evidence entries itemised.
RatTBIControlled cortical impactSprague-DawleyMaleLocal intraparenchymal administration2 x 10^5 cells24 hours after controlled cortical impact
Model: Moderate unilateral controlled cortical impact
Rats given local allogeneic adipose-derived mesenchymal stem cells 24 hours after controlled cortical impact showed improved motor test performance compared with both control groups. The cells were found in perilesional tissue with numbers declining over time after transplantation, and treatment in…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.
