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PRECLINICAL PUBLICATION · 2015

Puerarin attenuates smoke inhalation injury by regulation of Th1/Th2 expression and inhibition of Th17 cells in rats

Rat / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 26218281 ↗2015Reported benefit

Puerarin attenuates smoke inhalation injury by regulation of Th1/Th2 expression and inhibition of Th17 cells in rats

RatChemical/toxinWistarMale

Model: Gunpowder smog (smoke) inhalation producing acute lung injury

Puerarin reduced neutrophil infiltration and histological lung injury and lowered myeloperoxidase activity, relieved lung vascular permeability as judged by wet to dry weight ratio and lavage protein, decreased neutrophil and lymphocyte counts in bronchoalveolar lavage fluid compared with the untre…

Extraction: extract · Supplied extraction confidence: 0.62. Machine-extracted fields require source verification.