Alkontrol-herbal (Isoflavone) Effects on Alcohol Drinking in an Outpatient Setting
Alcohol Drinking · Alcohol Use Disorder · Alcohol Abstinence
Enrolment: 28 · Results not recorded
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Nutraceutical
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Alcohol Drinking · Alcohol Use Disorder · Alcohol Abstinence
Enrolment: 28 · Results not recorded
Metabolic Diseases · Obesity/Therapy
Enrolment: 80 · Results not recorded
Cardiovascular Disease Risk Factors
Enrolment: 217 · Results not recorded
Rheumatoid Arthritis
Enrolment: 119 · Results not recorded
Alcohol Abuse
Enrolment: 16 · Results not recorded
Alveolar Cleft Grafting
Enrolment: 20 · Results not recorded
Rheumatoid Arthritis
Enrolment: 150 · Results not recorded
Rheumatoid Arthritis
Enrolment: 150 · Results not recorded
Giant Cell Tumors
Enrolment: 145 · Results not recorded
Fatty Liver Disease
Enrolment: 118 · Results not recorded
6 studies reported at therapy level; 6 evidence entries itemised.
Model: Hypobaric hypoxia exposure causing acute lung and cerebral injury
Puerarin reduced hypobaric hypoxia-induced lung and cerebral tissue injury on histopathology and improved Morris water maze performance. Bronchoalveolar lavage inflammatory cytokines fell in both preventative groups. Aquaporin 1 and aquaporin 4 were raised by hypobaric hypoxia and downregulated by…
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.
Model: Acute spinal cord injury induced by a modified Allen's weight-drop method
Puerarin increased Basso-Beattie-Bresnahan score, attenuated histological injury, reduced neuronal loss, inhibited glial activation, lowered inflammation and apoptosis, and restored downregulated PI3K and phospho-Akt expression.
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.
Model: Gunpowder smog (smoke) inhalation producing acute lung injury
Puerarin reduced neutrophil infiltration and histological lung injury and lowered myeloperoxidase activity, relieved lung vascular permeability as judged by wet to dry weight ratio and lavage protein, decreased neutrophil and lymphocyte counts in bronchoalveolar lavage fluid compared with the untre…
Extraction: extract · Supplied extraction confidence: 0.62. Machine-extracted fields require source verification.
Model: Acute spinal cord ischaemia-reperfusion injury
Puerarin improved motor deficit and lowered glutamate levels and mGluR-1 mRNA expression after spinal cord ischaemia-reperfusion injury.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.
Model: Acute high-altitude hypobaric hypoxia induced brain injury produced in a hypobaric simulation chamber
Intranasal puerarin thermosensitive in situ hydrogel improved spatial memory and spontaneous exploratory behaviour, lowered malondialdehyde and glutathione in the peripheral circulation, reduced cerebral histological lesions and hypoxia-inducible factor-1alpha expression. It was absorbed rapidly (T…
Extraction: extract · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.
Model: Third-degree burn over 30% of total body surface area with lactated Ringer's solution resuscitation
Puerarin reduced the burn-induced rise in serum creatine kinase MB and cardiac troponin T, improved cardiomyocyte ultrastructure, lowered serum TNF-alpha (control value 1.09 plus or minus 0.09 ng/ml, peaking at 12 h post burn in the burn group), suppressed cardiac myeloperoxidase activity and malon…
Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.