Tranilast reduces serum IL-6 and IL-13 and protects against thioacetamide-induced acute liver injury and hepatic encephalopathy.

Tranilast reduces serum IL-6 and IL-13 and protects against thioacetamide-induced acute liver injury and hepatic encephalopathy.

Model: Thioacetamide-induced acute liver injury with hepatic encephalopathy

Tranilast improved hepatic function, restored oxidant/antioxidant balance, lowered serum nitric oxide, IL-6 and IL-13, reduced serum ammonia and decreased astrocyte swelling and vacuolisation.

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