Low-Magnitude, High-Frequency Vibration Fails to Accelerate Ligament Healing but Stimulates Collagen Synthesis in the Achilles Tendon.
RatOtherSprague-DawleyFemalen = 32 rats in two groups of 16; biomechanics 14 joint pairs pe…Whole-body vibration on a platform coupled to an electromagnetic shaker, with weightbearing on both limbs0.3 g peak-to-peak acceleration at 30 Hz, platform displace…Started 2 days after operation
Model: Complete surgical transection of the left medial collateral ligament at the midsubstance, with immediate weightbearing allowed
Vibration did not change ultimate tensile load (injured p = 0.925) or structural stiffness (p = 0.542) of the transected ligament, nor histological appearance. In the intact Achilles tendon of the injured limb, vibration increased collagen 1 alpha 3-fold, interleukin 6 7-fold, cyclooxygenase-2 5-fo…
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