Attenuated Reactive Gliosis and Enhanced Functional Recovery Following Spinal Cord Injury in Null Mutant Mice of Platelet-Activating Factor Receptor.
MouseSpinal cord injuryHemisection / partialC57BL/6 wild-type and platelet-activating factor receptor null mutantFemaleTreatment at the chronic phase improved recovery; treatment at the acute phase…
Model: Cervical spinal cord dorsal laceration injury
Platelet-activating factor receptor null mutant mice showed better grip and rotarod recovery, lower interleukin 6, vimentin, nestin and GFAP, and reduced proteoglycan deposition than wild-type injured mice. Ginkgolide B improved functional recovery in wild-type injured mice when given in the chroni…
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