Contusive spinal cord injury up regulates mu-opioid receptor (mor) gene expression in the brain and down regulates its expression in the spinal cord: possible implications in spinal cord injury research.

Contusive spinal cord injury up regulates mu-opioid receptor (mor) gene expression in the brain and down regulates its expression in the spinal cord: possible implications in spinal cord injury research.

Model: Standardised MASCIS (Multicenter Animal Spinal Cord Injury Study) contusive spinal cord injury

Naloxone produced negligible and statistically insignificant neuroprotection after contusive spinal cord injury. Mu-opioid receptor gene expression was upregulated in the brain but downregulated in the spinal cord after injury, which the authors propose explains the failure of naloxone in the NASCI…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.