Fresh frozen plasma and spray-dried plasma mitigate pulmonary vascular permeability and inflammation in hemorrhagic shock.
MouseHaemorrhage/shockControlledC57BL/6MaleResuscitation after haemorrhagic shock
Model: Haemorrhagic shock and trauma
FFP and SDP performed similarly, preserving endothelial monolayer integrity in vitro, reducing pulmonary vascular permeability, correcting mean arterial pressure and base excess, and reducing alveolar wall thickening, leukocyte infiltration and endothelial junction breakdown, whereas lactated Ringe…
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