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PRECLINICAL PUBLICATION · 2015

Hyperbaric oxygen effects on neuronal apoptosis associations in a traumatic brain injury rat model.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25982374 ↗2015Reported benefit

Hyperbaric oxygen effects on neuronal apoptosis associations in a traumatic brain injury rat model.

RatTBIUnspecifiedSprague-DawleyMaleInhaled, hyperbaric chamber100% O2 at 2.0 absolute atmospheres for 1 hourImmediately after traumatic brain injury

Model: Traumatic brain injury, specific impact method not stated in abstract

Hyperbaric oxygen improved running speed, reduced local and systemic TNF-alpha, neuronal damage score and neuronal apoptosis, lowered TGIF and increased TGF-beta1 expression 72 h after injury.

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.