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PRECLINICAL PUBLICATION · 2015

Resveratrol attenuates spinal cord injury-induced inflammatory damage in rat lungs.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25973008 ↗2015Reported benefit

Resveratrol attenuates spinal cord injury-induced inflammatory damage in rat lungs.

RatSpinal cord injuryContusionSprague-DawleyFemaleIntraperitoneal100 mg/kgImmediately after trauma

Model: Weight-drop impact spinal cord injury at the T10 vertebral level with remote lung inflammatory damage

Resveratrol alleviated spinal cord injury-induced pulmonary oedema, reduced neutrophil infiltration and inflammatory mediator production, upregulated SIRT1 and suppressed NF-kB activity in lung tissue.

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.