Neuroprotective effect of ketamine on acute spinal cord injury in rats.
RatSpinal cord injuryUnspecifiedSprague-DawleyMalen = 70 rats total (sham 10, control 30, treatment 30)IntraperitonealAfter injury
Model: Moderate acute spinal cord injury in rats
Ketamine-treated rats had significantly lower TNF-alpha, IL-6 and malondialdehyde levels and fewer TUNEL-positive cells than saline controls at each time point.
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