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PRECLINICAL PUBLICATION · 2015

Delayed Methylene Blue Improves Lesion Volume, Multi-Parametric Quantitative Magnetic Resonance Imaging Measurements, and Behavioral Outcome after Traumatic Brain Injury.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25961471 ↗2015Reported benefit

Delayed Methylene Blue Improves Lesion Volume, Multi-Parametric Quantitative Magnetic Resonance Imaging Measurements, and Behavioral Outcome after Traumatic Brain Injury.

RatTBIControlled cortical impactSprague-DawleyMaleDelayed treatment 24 h after injury, compared with acute treatment at 1 and 3 h…

Model: Controlled cortical impact to the primary forelimb somatosensory cortex in rats

Methylene blue given 24 h after injury still reduced lesion volume and functional deficits relative to vehicle.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.