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PRECLINICAL PUBLICATION · 2015

Enhancement of acute tendon repair using chitosan matrix.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25950535 ↗2015Reported benefit

Enhancement of acute tendon repair using chitosan matrix.

RatOtherWistarn = 40 Wistar rats, bilateral shoulders (80 repairs)Local application of gel between the tendon ends at the repair siteAt the time of acute repair

Model: Bilateral supraspinatus tendon tenotomy followed by acute suture repair in rats

Gel-augmented repairs showed more fibroblasts and repair tissue, minimal monocytic or inflammatory infiltrate around the matrix, and significantly improved pennation angles and fatty atrophy compared with suture-only controls.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.