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PRECLINICAL PUBLICATION · 2015

The effects of caffeic acid phenethyl ester on inflammatory cytokines after acute spinal cord injury.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25904269 ↗2015Reported benefit

The effects of caffeic acid phenethyl ester on inflammatory cytokines after acute spinal cord injury.

RatSpinal cord injuryCompressionWistar-AlbinoMalen = 48 rats in three groups, each split into two subgroupsSystemic administration30 minutes after trauma

Model: Acute spinal cord injury by aneurysm clip compression after lower thoracic laminectomy

CAPE suppressed serum TNF-alpha and IL-1beta after acute spinal cord injury and reduced histopathological haemorrhage and necrosis in the early phase.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.