Radioprotective effects of Sipunculus nudus L. polysaccharide combined with WR-2721, rhIL-11 and rhG-CSF on radiation-injured mice.
MouseRadiationICR (Imprinting Control Region)malen = 70 mice divided into seven groups
Model: Acute radiation injury from whole-body exposure to a 5 Gy cobalt-60 gamma-ray beam
Combined administration of SNP with WR-2721, rhIL-11 and rhG-CSF produced synergistic recovery of peripheral WBC, RBC and platelet counts and haemoglobin, and synergistic promotion of spleen, thymus, testicle, bone marrow nucleated cell and sperm counts. Serum SOD activity and testosterone increase…
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.