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PRECLINICAL PUBLICATION · 2015

Effects of Wharton's jelly cells of the human umbilical cord on acute spinal cord injury in rats, and expression of interleukin-1beta and nerve growth factor in spinal cord tissues.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25801039 ↗2015Reported benefit

Effects of Wharton's jelly cells of the human umbilical cord on acute spinal cord injury in rats, and expression of interleukin-1beta and nerve growth factor in spinal cord tissues.

RatSpinal cord injuryUnspecifiedSprague-DawleyFemalen = 81 rats in total, 27 per group

Model: Acute spinal cord injury

Transplanted rats showed better motor recovery and more intact spinal cord tissue than the model group, with significantly lower interleukin-1beta and higher nerve growth factor expression (p<0.05).

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.