Evidence & regulatory context
- Mechanism
- Not recorded
- Target
- Not recorded
- Injury models
- Spinal cord injury
- Reported indication
- Not recorded
- First approval
- Not recorded
- Development stage
- Not recorded
- ChEMBL record
- Not recorded
- ChEMBL max phase
- Not recorded
- Synonyms
- Not recorded
- Note
- Not recorded
Clinical trials 9
2 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
The Effect of Intrathecal Transplantation of Umbilical Cord Mesenchymal Stem Cells in Patients With Late Stage of Chronic Spinal Cord Injury: A Multicenter, Prospective, Cohort Study
Spinal Cord Injuries
Enrolment: 43 · Results not recorded
Guttmann NeuroRecovery - Viability, Safety, and Efficacy of Intrathecal Wharton's Jelly Mesenchymal Stem Cells and Transcutaneous Spinal Cord Stimulation in Chronic Spinal Cord Injury Rehabilitation: A Pilot Study
Spinal Cord Injuries (SCI) · Traumatic Spinal Cord Injuries
Enrolment: 10 · Results not recorded
Treatment of Respiratory Complications Associated With COVID-19 Infection Using Wharton's Jelly (WJ)-Umbilical Cord (UC) Mesenchymal Stromal Cells (ProTrans): a Randomized Phase II Controlled Clinical Trial
Covid19
Enrolment: 19 · Results not recorded
Phase I/II Study of Umbilical Cord Mesenchymal Stem Cell Implantation in the Treatment of Articular Cartilage Defect of Knee and Knee Osteoarthritis
Cartilage Damage · Degenerative Osteoarthritis
Enrolment: 20 · Results not recorded
Safety and Exploratory Efficacy Study of UCMSCs in Patients With Ischemic Heart Disease (SEESUPIHD)
Acute Myocardial Infarction · Ischemic Cardiomyopathy
Enrolment: 64 · Results not recorded
A Phase I Study To Evaluate the Safety of Umbilical Cord-Derived, Ex-Vivo Cultured and Expanded Wharton's Jelly Mesenchymal Stem Cells for the Treatment of De Novo High Risk Acute or Steroid Refractory Acute Graft Versus Host Disease
Acute Graft Versus Host Disease
Enrolment: 24 · Results not recorded
Collagen Scaffolds Loaded With Human Umbilical Cord Mesenchymal Stem Cells for the Improvement of Erectile Function in Men With Diabetes
Erectile Dysfunction · Type 1 Diabetes Mellitus · Type 2 Diabetes Mellitus
Enrolment: 0 · Results not recorded
Clinical Study of Umbilical Cord Mesenchymal Stem Cells as First-line Treatment for Patients With Acute Graft Versus Host Disease
aGVHD
Enrolment: 182 · Results not recorded
Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Knee Osteoarthritis
Knee Osteoarthritis
Enrolment: 50 · Results not recorded
Preclinical evidence 1
1 studies reported at therapy level; 1 evidence entries itemised.
RatSpinal cord injuryUnspecifiedSprague-DawleyFemalen = 81 rats in total, 27 per group
Model: Acute spinal cord injury
Transplanted rats showed better motor recovery and more intact spinal cord tissue than the model group, with significantly lower interleukin-1beta and higher nerve growth factor expression (p<0.05).
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.
