The effect of granulocyte-colony stimulating factor on rotator cuff healing after injury and repair.
RatOtherSprague-DawleyFemalen = 52 rats randomised to control or G-CSF, euthanised at 12 or…Systemic administrationStarted after rotator cuff repair
Model: Creation of a full-thickness supraspinatus tendon defect with immediate surgical repair
G-CSF significantly increased the cellularity composite score versus control at 12 days (7.40 plus or minus 1.14 versus 4.50 plus or minus 0.57, p = 0.038) and 19 days (8.00 plus or minus 1.00 versus 5.40 plus or minus 0.89, p = 0.023). No differences were seen in any biomechanical property or MRI…
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