Comparison and efficacy of LigaSure and rubber band ligature in closing the inflamed cecal stump in a rat model of acute appendicitis.
RatOtherSprague-DawleyMalen = 8 rats per subgroup in the day 8 group; group A subgroup si…Intra-operative surgical application to the caecal stump and mesocaecum, leaving about 1 mm of distal stump unburiedAt caecal resection, 24 h after caecal ligation
Model: Caecal ligation with 3-0 silk about 5 mm proximal to the caecal tip to produce obstruction, inflammation and gangrenous change, with caecal resection 24 h later to mimic appendectomy
LigaSure matched silk and outperformed rubber band ligature: at day 8 grade 4 adhesion occurred in 12.5 per cent of LigaSure animals versus 50 per cent for silk and 75 per cent for rubber band (p = 0.024), and hydroxyproline was highest with LigaSure (155.6 plus or minus 35.4 versus 106.8 plus or m…
Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.