PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2015

Evaluation of the effects of ischemic preconditioning on the hematological parameters of rats subjected to intestinal ischemia and reperfusion.

Rat / Ischaemia-reperfusion

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25672431 ↗2015Reported benefit

Evaluation of the effects of ischemic preconditioning on the hematological parameters of rats subjected to intestinal ischemia and reperfusion.

RatIschaemia-reperfusionIntestinal / mesentericWistarMalen = 40 rats total, n=10 per group in four groupsSurgical clamping of the superior mesenteric artery10 min superior mesenteric artery occlusion followed by 10…Immediately before the 45 min index ischaemia

Model: Superior mesenteric artery occlusion for 45 min followed by 120 min of reperfusion (intestinal ischaemia-reperfusion)

Preconditioning reduced granulocyte count and plateletcrit and increased lymphocyte count and mean platelet volume relative to ischaemia-reperfusion alone, and restored mean corpuscular haemoglobin concentration, suggesting attenuation of the circulating cell response to intestinal ischaemia-reperf…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.95. Machine-extracted fields require source verification.