PRECLINICAL PUBLICATION · 2014

Monitoring of Short-Term Erythropoietin Therapy in Rats with Acute Spinal Cord Injury Using Manganese-Enhanced Magnetic Resonance Imaging.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Recombinant human erythropoietin (rhEPO)

PMID 25510176 ↗2014Reported benefit

Monitoring of Short-Term Erythropoietin Therapy in Rats with Acute Spinal Cord Injury Using Manganese-Enhanced Magnetic Resonance Imaging.

RatSpinal cord injuryUnspecifiedSprague-DawleyMale

Model: Laminectomy at T11 followed by spinal cord injury

Erythropoietin-treated rats showed significantly better functional recovery, higher manganese-enhanced MRI signal-to-noise ratio at the lesion epicentre, and fewer microglia and apoptotic cells.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.