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PRECLINICAL PUBLICATION · 2015

The effect of coenzyme Q10 on the regeneration of crushed facial nerve.

Rat / Crush

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25490571 ↗2015Reported benefit

The effect of coenzyme Q10 on the regeneration of crushed facial nerve.

RatCrushPeripheral-nerve crushSprague-Dawley albinoFemalen = 16 rats in total, 8 per groupIntraperitoneal10 mg/kg/dayStarted after facial nerve crush

Model: Crush injury of the right facial nerve

Coenzyme Q10 produced greater improvement in stimulation threshold than saline and significantly better vascular congestion, macrovacuolisation and myelin thickness, although neither group returned to pre-crush amplitude.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.