ACE inhibition attenuates radiation-induced cardiopulmonary damage.
RatRadiationWistarMaleOralStarted after local irradiation
Model: Local irradiation of the rat heart and/or lungs, with endpoints at 8 weeks
Captopril improved breathing rate, cardiopulmonary density and structure and left ventricular end-diastolic pressure and reduced effusions and cardiac fibrosis, but only when the heart was included in the radiation field.
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.