Protective effect of Cucurbita pepo fruit peel against CCl4 induced neurotoxicity in rat.
RatChemical/toxinSprague-DawleyFemalen = 36 rats in 6 groups of 6200 and 400 mg/kg body weightCo-treatment with CCl4 over the same two-week dosing period
Model: Carbon tetrachloride induced acute neurotoxicity, 20% CCl4 in corn oil at 1 ml/kg body weight intraperitoneally
Co-treatment with Cucurbita pepo fruit peel methanol extract restored brain antioxidant enzyme activities and reduced lipid peroxidation after carbon tetrachloride intoxication in a dose-dependent manner.
Extraction: extract · Supplied extraction confidence: 0.72. Machine-extracted fields require source verification.