PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2014

Dietary glutamine prevents the loss of intestinal barrier function and attenuates the increase in core body temperature induced by acute heat exposure.

Mouse / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25322775 ↗2014Reported benefit

Dietary glutamine prevents the loss of intestinal barrier function and attenuates the increase in core body temperature induced by acute heat exposure.

MouseOtherSwissMaleOral, as a dietary supplement to an isoenergetic and isoproteic AIN-93G dietFed for 7 days before the heat exposure trial

Model: Acute heat stress by exposure to a high ambient temperature of 39 degrees C for 2 h, causing intestinal barrier dysfunction and bacterial translocation

Dietary glutamine supplementation attenuated heat-induced hyperthermia and prevented the increases in intestinal permeability and bacterial translocation, with no correlation between the two effects.

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.