Effects of ozonated olive oil on acute radiation proctitis in rats.
RatRadiationRectal (topical)1 mL per administrationStarting after irradiation
Model: Acute radiation proctitis induced by a single 17.5 Gy fraction of pelvic irradiation
Five rats in the irradiation plus saline group showed Grade 4 clinical symptoms by day 10, and radiation-induced mucosal damage was most prominent at day 10 in saline-treated animals. Macroscopic finding scores at day 10 differed significantly between the irradiation plus saline and irradiation plu…
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