PRECLINICAL PUBLICATION · 2014

Transplanted Human Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells Do Not Promote Functional Recovery of Pharmacologically Immunosuppressed Mice With Contusion Spinal Cord Injury.

Mouse / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Human induced pluripotent stem cell-derived neural progenitor cells, with tacrolimus immunosuppression

PMID 25203632 ↗2014No effect reported

Transplanted Human Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells Do Not Promote Functional Recovery of Pharmacologically Immunosuppressed Mice With Contusion Spinal Cord Injury.

MouseSpinal cord injuryContusionC57BL/6JFemaleIntraspinal transplantation into the contused spinal cordSubacute phase after contusion injury

Model: Contusion spinal cord injury

Human iPSC-derived neural progenitor cells transplanted into pharmacologically immunosuppressed mice showed poor long-term survival and did not improve functional recovery compared with vehicle.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.