Curcumin improves the recovery of motor function and reduces spinal cord edema in a rat acute spinal cord injury model by inhibiting the JAK/STAT signaling pathway.
RatSpinal cord injuryContusionSprague-DawleyMaleIntraperitoneal40 mg/kg30 minutes after injury
Model: Acute spinal cord injury induced by a falling weight
Curcumin moderately improved locomotor recovery and reduced haemorrhage, oedema and neutrophil infiltration, with reduced aquaporin-4 and GFAP expression and suppressed JAK/STAT activation.
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.