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PRECLINICAL PUBLICATION · 2014

High-dose ascorbic acid administration improves functional recovery in rats with spinal cord contusion injury.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25179654 ↗2014Reported benefit

High-dose ascorbic acid administration improves functional recovery in rats with spinal cord contusion injury.

RatSpinal cord injuryContusionSprague-DawleyFemalen = 30 rats, 10 per group across three groupsIntraperitoneal100 mg/kg body weight (normal dose) or 200 mg/kg body weigh…Acute phase after spinal cord injury

Model: Standardised spinal cord contusion injury

High-dose ascorbic acid improved BBB score at days 14 and 28 and improved gait parameters compared with control and normal dose. Both doses reduced necrosis at the injury site.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.