Photoprotection of Buddleja cordata extract against UVB-induced skin damage in SKH-1 hairless mice.
MouseRadiationSKH-1 hairlessFemalen = 25 mice, five groups of five mice each; a further n = 5 for…Topical application to dorsal skin200 µL of a 2 mg/mL ethanolic solution applied to a 6 cm2 d…15 minutes before UVB irradiation
Model: Acute UVB-induced skin damage: dorsal skin irradiated with UVB lamps (302 nm, 6 W) positioned 15 cm above the back, delivering 6 mJ/cm2 over a 10-minute exposure
Topical BCME protected against acute UVB-induced skin damage. Irradiated BCME-treated mice showed less redness than irradiated vehicle controls, and skin from the BCME plus UVB group showed only slight epidermal thickening with no vessel congestion or epidermal and dermal oedema, and fewer sunburn…
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