Blood sulfhydryl level increases during hyperoxia: a marker of oxidant lung injury.
RatOtherMalePretreatment before hyperoxic exposure
Model: Normobaric hyperoxia for 48 h or more causing acute oedematous lung injury
Hyperoxia raised blood acid-soluble sulfhydryl levels in parallel with lung oxidised glutathione and GSSG-to-GSH ratio. Pretreatment with dimethylthiourea reduced the rises in blood sulfhydryl, haematocrit, pleural effusion volume, lung GSSG and GSSG-to-GSH ratio.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.