Heat stress protects against mechanical ventilation-induced diaphragmatic atrophy.
RatOtherWistarMalen = n = 38 adult male Wistar rats across four groupsWhole-body heating1 h heat stress applied 24 h before mechanical ventilation
Model: 12 h controlled mechanical ventilation causing diaphragmatic atrophy
Heat stress increased diaphragmatic HSP72 and attenuated ventilation-induced atrophy of type I, IIa and IIx fibres, but did not protect against ventilation-induced diaphragm contractile dysfunction.
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