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PRECLINICAL PUBLICATION · 2014

A single dose of platelet-rich plasma improves the organization and strength of a surgically repaired rotator cuff tendon in rats.

Rat / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 25027676 ↗2014Reported benefit

A single dose of platelet-rich plasma improves the organization and strength of a surgically repaired rotator cuff tendon in rats.

RatWoundWistarMalen = 44 Wistar rats in two groups, with 12 rats per group for bi…Intra-articular injection into the shoulderSingle dose, volume not statedImmediately after the surgical repair

Model: Experimental acute rotator cuff tear with surgical suture repair, assessed at 3 weeks

Platelet-rich plasma increased maximal load (p < 0.001) and stiffness (p < 0.005), improved Bonar score (p = 0.018) and collagen organisation by birefringence (p = 0.002) at 3 weeks, with no difference in vascularity.

Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.