Exercise modulates chloride homeostasis after spinal cord injury.
RatSpinal cord injuryComplete transectionSprague DawleyFemaleApplied after transection in the SCI-14d plus exercise and SCI-28d plus exercis…
Model: Complete spinal cord transection at T12
Exercise returned spinal excitability and KCC2 and NKCC1 levels towards normal in the lumbar spinal cord. Blocking KCC2 with DIOA masked the effect of exercise on frequency-dependent depression, while bumetanide returned FDD towards intact levels after injury.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.