Effect of atorvastatin on wound healing in rats.
RatWoundMaleTopical, oral, or both
Model: Acute 8 mm punch excision wound in the dorsal region under anaesthesia
Lesion areas were significantly reduced in all atorvastatin-treated groups compared with placebo, with increased IRS-1, PI3K, Akt, GSK-3 and IL-10 expression and lower IL-6 and TNF-alpha on days 1, 3 and 7.
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.