PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2014

Effect of amiloride on endoplasmic reticulum stress response in the injured spinal cord of rats.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 24905230 ↗2014Reported benefit

Effect of amiloride on endoplasmic reticulum stress response in the injured spinal cord of rats.

RatSpinal cord injuryContusionSprague-DawleyFemaleAcute phase after injury

Model: Traumatic spinal cord contusion injury

Amiloride significantly improved hindlimb function, decreased CHOP and apoptosis, increased GRP78 and raised NG2-positive oligodendrocyte precursor cell numbers in the injured cord.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.