Effect of Amiloride and Spironolactone on Renophysiological and Cardiovascular Variables in Patients With Essential Hypertension
Hypertension
Enrolment: 23 · Results not recorded
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Drug · Amiloride-sensitive sodium channel, ENaC blocker (BLOCKER)
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Hypertension
Enrolment: 23 · Results not recorded
Hypertension
Enrolment not recorded · Results not recorded
Chronic Kidney Disease(CKD) · Proteinuria
Enrolment: 40 · Results not recorded
Heart Failure
Enrolment: 50 · Results not recorded
Low-Renin Hypertension
Enrolment: 30 · Results not recorded
Diabetic Nephropathies · Hypertension
Enrolment: 80 · Results not recorded
Hypertension
Enrolment: 0 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Traumatic spinal cord contusion injury
Amiloride significantly improved hindlimb function, decreased CHOP and apoptosis, increased GRP78 and raised NG2-positive oligodendrocyte precursor cell numbers in the injured cord.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.