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PRECLINICAL PUBLICATION · 2014

Protective effect of polydatin against burn-induced lung injury in rats.

Rat / Burn

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 24825914 ↗2014Reported benefit

Protective effect of polydatin against burn-induced lung injury in rats.

RatBurnUnspecifiedSprague-Dawleymale45 mg/kgAfter burn injury and resuscitation

Model: Thermal burn covering 30 percent total body surface area followed by resuscitation, with secondary acute lung injury

Polydatin reduced pulmonary microvascular permeability, wet-to-dry ratio, myeloperoxidase activity, pro-inflammatory cytokines and apoptosis after burn injury.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.