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PRECLINICAL PUBLICATION · 2014

Extracellular matrix-regulated neural differentiation of human multipotent marrow progenitor cells enhances functional recovery after spinal cord injury.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 24792783 ↗2014Reported benefit

Extracellular matrix-regulated neural differentiation of human multipotent marrow progenitor cells enhances functional recovery after spinal cord injury.

RatSpinal cord injuryUnspecifiedn = 24 animals randomised to four groups with 6 per groupTwo bilateral injections into the lesion siteAfter spinal cord injury

Model: Acute spinal cord injury with bilateral injection into the lesion site

Tenascin-cytotactin with cytokines enhanced neuronal marker expression and produced significant functional repair by day 42, whereas chondroitin sulfate reduced neuronal marker expression.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.