Evidence & regulatory context
- Mechanism
- Not recorded
- Target
- Not recorded
- Injury models
- Spinal cord injury
- Reported indication
- Not recorded
- First approval
- Not recorded
- Development stage
- Not recorded
- ChEMBL record
- Not recorded
- ChEMBL max phase
- Not recorded
- Synonyms
- Not recorded
- Note
- Not recorded
Clinical trials 5
1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
A Multicenter Trial of Autologous Bone Marrow Mononuclear Cells for the Treatment of Adult Severe Traumatic Brain Injury
Brain Injuries, Traumatic · Brain Injuries, Acute · TBI (Traumatic Brain Injury)
Enrolment: 37 · Results not recorded
CHOA-AML: A Pilot Study for Newly Diagnosed Pediatric Patients With Acute Myeloid Leukemia (AML)
Acute Myeloid Leukemia · AML, Childhood
Enrolment: 8 · Results not recorded
Safety and Efficacy Study of Traumatic Bone Defects Treatment With Use of 3D Tissue Engineered Equivalent.
Bone Defects
Enrolment: 20 · Results not recorded
Effectiveness and Safety of Intravenous Infusion of Bone Marrow Derived Allogeneic Multipotent Mesenchymal Stromal Cells for Enhancing Hematopoietic Recovery and Prophylaxis of Neutropenic Enterocolitis in Hematological Patients With Aplasia After High-dose Chemotherapy.
Neutropenic Enterocolitis · Myeloablative Chemotherapy Induced Bone Marrow Aplasia
Enrolment: 16 · Results not recorded
Phase I/II Trial of Autologous Bone Marrow Derived Mesenchymal Stem Cells to Patients With Parkinson's Disease.
Parkinson's Disease
Enrolment: 20 · Results not recorded
Preclinical evidence 1
1 studies reported at therapy level; 1 evidence entries itemised.
RatSpinal cord injuryUnspecifiedn = 24 animals randomised to four groups with 6 per groupTwo bilateral injections into the lesion siteAfter spinal cord injury
Model: Acute spinal cord injury with bilateral injection into the lesion site
Tenascin-cytotactin with cytokines enhanced neuronal marker expression and produced significant functional repair by day 42, whereas chondroitin sulfate reduced neuronal marker expression.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.
