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PRECLINICAL PUBLICATION · 2014

Systemic effects of TRAIL (TNF-related apoptosis-inducing ligand) during acute gamma-irradiation.

Mouse / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 24771425 ↗2014Reported benefit

Systemic effects of TRAIL (TNF-related apoptosis-inducing ligand) during acute gamma-irradiation.

MouseRadiation101/Hf and C3H/SnMaleIntravenous injection

Model: Acute whole-body gamma irradiation at 750 R

TRAIL attenuated irradiation-induced changes in body weight, plasma subfractions, open field activity, intestinal and hepatic tissue injury and thymic Hassall's corpuscle content, with the degree of change differing between the two mouse strains.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.