Direct intrawound administration of dimethylsulphoxide relieves acute pain in rats.
RatWoundSprague-DawleyMaleIntrawound administration into the incision site10 microlitres of 100% DMSOJust before closure of the wound
Model: Hind-paw incision wound model of acute pain
A single 10 microlitre intrawound dose of 100% DMSO persistently attenuated guarding behaviour over 3 days without affecting thermal hyperalgesia or allodynia, and wound healing was normal at the end of the study.
Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.