Beneficial effects of methylene blue on the acute phase of corrosive esophageal burn in rats.
RatBurnChemical / corrosiveSprague-DawleyMalen = 21 rats, 7 per group across three groupsLocal application to the distal oesophageal lumen30 mg/kg90 min after the burn
Model: Corrosive alkali burn of the distal oesophagus with 30 per cent sodium hydroxide solution
Methylene blue raised tissue superoxide dismutase and total antioxidant status, lowered total oxidant status and significantly attenuated histopathological damage in the acute phase of corrosive oesophageal burn.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.