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PRECLINICAL PUBLICATION · 2013

Thoracic duct ligation in the rat attenuates lung injuries in acute pancreatitis.

Rat / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 24645537 ↗2013Reported benefit

Thoracic duct ligation in the rat attenuates lung injuries in acute pancreatitis.

RatChemical/toxinWistarMalen = 34 rats: thoracic duct ligation n=8, acute pancreatitis n=8…Ligation performed two days before induction of pancreatitis

Model: Cerulein-induced acute pancreatitis with secondary lung injury

Prior thoracic duct ligation attenuated lung damage, myeloperoxidase activity, IL-6 and angiopoietin-2 in cerulein-induced acute pancreatitis, while pancreatic and ileal damage were unchanged.

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.