THERAPY DOSSIER · th-6055d8ae3b29

Thoracic duct ligation

Procedure

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Chemical/toxin
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 1

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT06995599 ↗NAnot yet recruiting

Thoracic Duct Ligation and Postoperative Weight Loss in Obese Patients Undergoing Minimally Invasive Lung Surgery: A Pilot Exploratory Clinical Study

Obese Patients

Enrolment: 16 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 24645537 ↗2013Reported benefit

Thoracic duct ligation in the rat attenuates lung injuries in acute pancreatitis.

RatChemical/toxinWistarMalen = 34 rats: thoracic duct ligation n=8, acute pancreatitis n=8…Ligation performed two days before induction of pancreatitis

Model: Cerulein-induced acute pancreatitis with secondary lung injury

Prior thoracic duct ligation attenuated lung damage, myeloperoxidase activity, IL-6 and angiopoietin-2 in cerulein-induced acute pancreatitis, while pancreatic and ileal damage were unchanged.

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.

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