Assessment of depression in a rodent model of spinal cord injury.
RatSpinal cord injuryContusionSprague-Dawleymalen = 26 subjects in the first experiment, of which 9 met depress…Given in a second experiment to subjects classified as depressed on days 9 to 1…
Model: Rodent contusion spinal cord injury
A behavioural battery identified a depression-like cluster in 9 of 26 contused rats. Fluoxetine significantly decreased forced swim test immobility in depressed subjects identified by the discriminant function, whereas depressed saline-treated subjects showed significantly increased immobility rela…
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