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PRECLINICAL PUBLICATION · 2014

Protective effect of chitosan from Sepia kobiensis (Hoyle 1885) cuttlebone against CCl4 induced hepatic injury.

Rat / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 24530330 ↗2014Reported benefit

Protective effect of chitosan from Sepia kobiensis (Hoyle 1885) cuttlebone against CCl4 induced hepatic injury.

RatChemical/toxinWistar

Model: Carbon tetrachloride-induced hepatic injury with hepatic necrosis

Chitosan lowered aminotransferase activities, cholesterol, triglycerides, free fatty acids and malondialdehyde, raised superoxide dismutase, catalase, glutathione peroxidase and reduced glutathione, and reduced histological liver damage.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.