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PRECLINICAL PUBLICATION · 2014

Neuroprotective effects of human spinal cord-derived neural precursor cells after transplantation to the injured spinal cord.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 24412492 ↗2014Mixed findings

Neuroprotective effects of human spinal cord-derived neural precursor cells after transplantation to the injured spinal cord.

RatSpinal cord injuryContusionFemaleTransplantation into the injured spinal cord9 days after contusion; immediately, 1 week or 7 weeks after compression

Model: Spinal contusion injury and spinal compression injury

Transplantation 9 days after contusion enhanced hindlimb recovery. After compression injury, transplantation immediately or at 1 week significantly improved recovery but transplantation at 7 weeks did not. No allodynia and no focal tumour growth were seen. Host neuron survival was highest in the ac…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.