Hyperbaric oxygen treatment produces an antinociceptive response phase and inhibits astrocyte activation and inflammatory response in a rat model of neuropathic pain.
RatOtherSprague-DawleyMalePostoperatively, with testing preoperatively and for 1 week after surgery
Model: Chronic constriction injury of the sciatic nerve
Rats showed transient allodynia immediately after hyperbaric oxygen, associated with changes in malondialdehyde and superoxide dismutase, while a single treatment produced a short-acting antinociceptive phase and repetitive treatment produced a long-acting antinociceptive phase with inhibition of a…
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.