The effects of luteolin on the intestinal ischemia/reperfusion injury in mice.
MouseIschaemia-reperfusionIntestinal / mesentericC57BL/6Femalen = 24 mice in 4 groups of 6IntraperitonealAdministered before reperfusion in the injury group, and 30 minutes after lapar…
Model: 30 minutes of superior mesenteric artery occlusion followed by 2 hours of reperfusion after laparotomy; sham animals had laparotomy only
Luteolin significantly reduced histological injury (p=0.037) and tissue total oxidant status (p=0.005) compared with untreated ischaemia-reperfusion, while total antioxidant capacity was unchanged (p>0.05).
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.